Siena Construction is a Cambridge-based general contractor with 35 years of experience delivering complex construction projects across Cambridge and Greater Boston. We specialize in technically demanding environments, including life science laboratories, commercial office interiors, academic campuses, healthcare facilities, historic buildings, and hospitality spaces. Our work is defined by careful coordination, technical understanding, and the ability to execute in active, occupied environments.

We provide construction and renovation services across a diverse range of sectors: Life science and laboratory construction (wet labs, dry labs, lab/office hybrid spaces); Commercial office tenant interiors and repositioning; Academic and university facilities, including research and teaching spaces; Healthcare and research institutes; Historic restorations and adaptive reuse projects; and Hospitality and amenity-driven environments. Each project is approached with an understanding of the specific operational, regulatory, and infrastructure requirements unique to the project.

Siena has a long-standing presence in Cambridge and Boston, working across dense urban environments, active campuses, and multi-tenant buildings. We regularly deliver projects in: Kendall Square and the broader Cambridge life science corridor; Downtown Boston and Back Bay commercial districts; University campuses and institutional facilities; and Mixed-use and historic properties throughout Greater Boston. Our familiarity with local building conditions, permitting processes, and logistical constraints allows us to execute projects efficiently and with minimal disruption.